Behavioral and biochemical effects of an ICV injection of streptozotocin in old Lewis rats
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منابع مشابه
Spatial learning deficit and reduced hippocampal ChAT activity in rats after an ICV injection of streptozotocin.
ICV injections of streptozotocin (STREP) lower the glucose utilization of the brain and affect the cholinergic system. The present study was designed to evaluate whether STREP-treated rats have an impaired spatial discrimination performance in the Morris spatial navigation task. Performance in this task is sensitive to treatment with cholinergic antagonists. In contrast to young rats, middle-ag...
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ژورنال
عنوان ژورنال: Pharmacology Biochemistry and Behavior
سال: 1994
ISSN: 0091-3057
DOI: 10.1016/0091-3057(94)90284-4